Migalastat HCl | Galactosidase inhibitor/Pharmacological chaperone
CAS:
75172-81-5
Catalog Number:
10-2632
CELLULAR METABOLISM
Daily function of cells involves many biochemical pathways that continuously monitor and balance energy homeostasis. Disruption of cellular metabolism can lead to diseases that affect most systems in the body. A hallmark of cancer, for example, is a restructuring of normal cellular metabolism to meet the energetic and stress demands inherent in rapid cell growth. Diseases that involve inborn errors of metabolism (IEM’s) include phenylketonuria, Niemann-Pick disease, and glycogen storage diseases.
Complex carbohydrates
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
Tunicamycin | ER stress inducer
CAS:
11089-65-9
Catalog Number:
10-2111
Activity:
ER stress inducer
Molecular Weight:
840.0 (Avg)
Molecular Formula:
C38H62N4O16 (tun. B)
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT
Glucose
Mito-lonidamine | Mitochondria-targeted antiglycolytic agent
CAS:
2361564-49-8
Catalog Number:
10-5492
CBR-470-1 | NRF2 signaling activator
CAS:
2416095-06-0
Catalog Number:
10-4680
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
Glutamine
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
Gilteritinib | FLT3 Inhibitor
CAS:
1254053-43-4
Catalog Number:
10-4170
Activity:
FLT3 inhibitor
Chemical Names:
6-Ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide; ASP2215
Molecular Weight:
552.72
Molecular Formula:
C29H44N8O3
Solubility:
Soluble in DMSO (25 mg/ml)
Physical Properties:
Off-white to pale pink solid
Purity:
>98% HPLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
GAC Inhibitor 968 | Glutaminase C inhibitor
CAS:
311795-38-7
Catalog Number:
10-1538
Activity:
Glutaminase C inhibitor
Chemical Names:
5-(3-bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]-phenanthridin-4(1H)-one
Molecular Weight:
475.42
Molecular Formula:
C27H27BrN2O
Solubility:
Soluble in DMSO (up to 11 mg/ml) or in Ethanol (up to 1 mg/ml with warming)
Physical Properties:
Off-white solid
Purity:
98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Glutathione
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
DT-109 | Induces glutathione biosynthesis
CAS:
14857-82-0
Catalog Number:
10-5732
Activity:
Induces glutathione biosynthesis
Chemical Names:
Glycyl-glycyl-L-leucine; Gly-Gly-Leu-OH
Molecular Weight:
245.28
Molecular Formula:
C10H19N3O4
Solubility:
Soluble in DMSO (25 mg/ml with warming); Water (25 mg/ml)
Physical Properties:
White solid
Purity:
>98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT
RSL3 | GPX4 inhibitor/Ferroptosis inducer
CAS:
1219810-16-8
Catalog Number:
10-3417
Activity:
GPX4 inhibitor/Ferroptosis inducer
Chemical Names:
(1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate
Alternate Name:
1S,3R-RSL3
Molecular Weight:
440.88
Molecular Formula:
C23H21ClN2O5
Solubility:
Soluble in DMSO (45 mg/ml)
Physical Properties:
Off-white solid
Purity:
>98% HPLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Shipping Code:
RT
Kinases
UNC7467 | IP6K inhibitor
CAS:
2922283-43-8
Catalog Number:
10-4080
CBR-470-1 | NRF2 signaling activator
CAS:
2416095-06-0
Catalog Number:
10-4680
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
Lipid Metabolism
S07-2010 | pan-AKR1C inhibitor
CAS:
1223194-71-5
Catalog Number:
10-4148
Bempedoic acid | ATP citrate lyase inhibitor
CAS:
738606-46-7
Catalog Number:
10-4114
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
Mitochondrial
Visomitin | Mitochondria-targeted antioxidant
CAS:
934826-68-3
Catalog Number:
10-3913
Mito-lonidamine | Mitochondria-targeted antiglycolytic agent
CAS:
2361564-49-8
Catalog Number:
10-5492
IACS-010759 | Mitochondrial Complex I Inhibitor
CAS:
1570496-34-2
Catalog Number:
10-4475
NAD
STF-118804 | NAMPT inhibitor
CAS:
894187-61-2
Catalog Number:
10-5640
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
P7C3-A20 | NAMPT activator/Proneurogenic agent
CAS:
1235481-90-9
Catalog Number:
10-3414
Activity:
NAMPT activator/proneurogenic agent
Chemical Names:
3,6-Dibromo-ß-fluoro-N-(3-methoxyphenyl)-9H-carbazole-9-propanamine
Molecular Weight:
506.21
Molecular Formula:
C22H19Br2FN2O
Solubility:
Soluble in DMSO (40 mg/ml)
Physical Properties:
Off-white solid
Purity:
>98% TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Nucleotide
Raltitrexed | Thymidylate synthase inhibitor
CAS:
112887-68-0
Catalog Number:
10-4052
Methylbenzoprim | Dual thymidylate synthase/dihydrofolate reductase inhibitor
CAS:
118344-71-1
Catalog Number:
10-4892
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
Polyamine
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
Mitoguazone 2HCl | Polyamine biosynthesis inhibitor / SAM decarboxylase inhibitor
CAS:
7059-23-6
Catalog Number:
10-4552
Activity:
Polyamine biosynthesis inhibitor / SAM decarboxylase inhibitor
Alternate Names:
MGBG
Chemical Name:
Methylglyoxal bis(guanylhydrazone) dihydrochloride
Molecular Weight:
257.13
Molecular Formula:
C5H12N8 2HCl
Solubility:
Soluble in Water (greater than 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Confirms)
NMR (Confirms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 1 month.
Shipping Code:
RT
POB | Ornithine decarboxylase inhibitor
CAS:
946135-39-3
Catalog Number:
10-4553
Activity:
Ornithine decarboxylase inhibitor
Chemical Name:
N-(4′-Pyridoxyl)-L-Ornithine(BOC)-Ome
Molecular Weight:
397.47
Molecular Formula:
C19H31N3O6
Solubility:
Soluble in DMSO (up to 25 mg/ml), in Water (up to 2 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Confirms)
NMR (Confirms)
Storage Temperature:
RT
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. Solutions in distilled water are not stable and must be made fresh and used within one working day.
Shipping Code:
RT
Sphingolipids
L-Cycloserine | Serine palmitoyltransferase inhibitor
CAS:
339-72-0
Catalog Number:
10-2280
PF-543 HCl | Sphingosine kinase-1 inhibitor
CAS:
1706522-79-3
Catalog Number:
10-4998
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
trans-Sulfuration
Intelliscreen™ Cancer Cell Metabolism Library
Catalog Number:
10-7101
Description:
171 modulators of various aspects of cancer cell metabolism.
Solubility:
DMSO or Water
Supplied As:
Compounds are supplied in either DMSO or water as dictated by solubility. Three plates supplied as DMSO solutions and one plate as water solutions.
Storage Temperature:
-80°C
Stability:
Stable for up to 1 year when stored as supplied @ -80°C
Price:
$4 600.00
PF-9366 | Methionine adenosyltransferase 2A inhibitor
CAS:
72882-78-1
Catalog Number:
10-4635
Activity:
Methionine adenosyltransferase 2A inhibitor
Chemical Name:
2-(7-Chloro-5-phenyl)-[1,2,4]triazolo[4,3-a]quinoline-1-yl)-N,N,dimethylethanamine
Molecular Weight:
350.85
Molecular Formula:
C20H19ClN4
Solubility:
Soluble in DMSO (up to 20 mg/ml).
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT
Propargylglycine | H2S synthase inhibitor
CAS:
64165-64-6
Catalog Number:
10-1366
Activity:
H2S synthase inhibitor
Chemical Name:
2-Amino-4-pentynoic acid
Molecular Weight:
113.12
Molecular Formula:
C5H7NO2
Solubility:
Soluble in DMSO (up to 10 mg/ml) or in Water (up tp 10 mg/ml).
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
Shipping Code:
RT
Other
Mirabegron | beta-3 Adrenergic agonist
CAS:
223673-61-8
Catalog Number:
10-4228
S07-2010 | pan-AKR1C inhibitor
CAS:
1223194-71-5
Catalog Number:
10-4148
SM-88 | Tyrosine metabolism inhibitor
CAS:
30625-05-9
Catalog Number:
10-4647
