The Protein kinase C family of serine/threonine kinases is involved in many cellular processes including gene transcription, cell growth and proliferation, membrane structure, and various immune responses. The family is divided into three main isozyme categories: Conventional (PKCα, ßI, ßII, γ requiring DAG and Ca2+), Novel (PKCδ, ε, η, Θ requiring just DAG), and atypical (PKCι, ζ requiring neither DAG nor Ca2+).